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Medical & Healthcare Franchise Opportunities Under $500k - Affordable Franchise Investment 2026

Explore proven Medical & Healthcare franchises under $500k across the USA and Canada. Find affordable, low-risk opportunities in home services, mobile businesses, cleaning, pet care, fitness, wellness, automotive, senior care, education, tutoring, kids’ activities, real estate services, marketing, retail, and food concepts. Compare investment ranges, fees, support, and territories. Ideal for entrepreneurs seeking a faster, lower-cost path to ownership in 2026
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Nuviva Medical Weight Loss
Medical & Healthcare Franchise Many Cities, Many States, USA

Nuviva Medical Weight Loss

Nuviva Medical Weight Loss is a physician-supervised medical weight loss and wellness franchise built for today’s health-conscious, results-driven consumers. The brand operates at the intersection of clinical care, lifestyle transformation, and aesthetics, offering structured programs that emphas...

2013Estd.
50Units
Min. Investment

$150,000

North Star Family Medicine
Medical & Healthcare Franchise Many Cities, Many States, USA

North Star Family Medicine

North Star Family Medicine represents a modern, patient-centered approach to primary healthcare in the United States—combining trusted family medicine principles with scalable, franchise-ready systems. Designed to meet the rising demand for accessible, preventative, and long-term care, North Star...

2010Estd.
15Units
Min. Investment

$350,000

Nora Mental Health
Medical & Healthcare Franchise Many Cities, Many States, USA

Nora Mental Health

Nora Mental Health is redefining how mental health services are delivered across the United States. Built around accessibility, clinical excellence, and a strong community-first approach, the brand provides outpatient behavioral health services that address one of the fastest-growing and most res...

2018Estd.
20Units
Min. Investment

$300,000

My Eyelab - Optical & Eye Care
Medical & Healthcare Franchise Many Cities, Many States, USA

My Eyelab - Optical & Eye Care

My Eyelab is a modern, fast-growing optical retail and eye-care franchise designed to meet the evolving needs of value-driven consumers across the United States. Built around a clear promise—quality eye care, affordable pricing, and a fast, convenient customer experience—the brand has positioned ...

2013Estd.
100Units
Min. Investment

$500,000

Medicap Pharmacy
Medical & Healthcare Franchise Many Cities, Many States, USA

Medicap Pharmacy

Medicap Pharmacy is a well-established community pharmacy franchise that blends personalized healthcare with the strength of a nationally recognized brand. Built on a patient-first philosophy, Medicap Pharmacy focuses on delivering trusted pharmaceutical services, medication management, immunizat...

1973Estd.
75Units
Min. Investment

$350,000

Liquivida Lounge
Medical & Healthcare Franchise Many Cities, Many States, USA

Liquivida Lounge

Liquivida Lounge has emerged as one of America’s fastest-growing wellness and IV therapy franchise brands, redefining how individuals invest in long-term vitality, preventative health, and luxury wellness experiences. Known for its modern, spa-like environment, science-backed treatments, and stro...

2013Estd.
30Units
Min. Investment

$250,000

Light Lounge Franchise Cost & Fees Opportunity
Medical & Healthcare Franchise Many Cities, Many States, USA

Light Lounge Franchise Cost & Fees Opportunity

Light Lounge is one of the fastest-growing wellness concepts in the United States, built around the surging demand for non-invasive, science-backed red light therapy. As more Americans prioritize preventative care, natural healing, and high-performance recovery, Light Lounge has positioned itself...

2019Estd.
10Units
Min. Investment

$250,000

Lifeologie Institute
Medical & Healthcare Franchise Many Cities, Many States, USA

Lifeologie Institute

Lifeologie Institute is a fast-growing mental health and counseling franchise built on a mission-driven model that blends clinical excellence with a warm, creative, client-centered culture. In a time when demand for mental health services continues to surge across the United States, Lifeologie st...

2000Estd.
25Units
Min. Investment

$120,000

Lice Lifters - Head Lice Removal
Medical & Healthcare Franchise Many Cities, Many States, USA

Lice Lifters - Head Lice Removal

Lice Lifters is one of America’s most recognized and trusted head-lice removal franchises, offering families fast, safe, and physician-recommended solutions during one of the most stressful moments of parenthood. Built on a science-driven, non-toxic treatment system and a warm, family-friendly se...

2010Estd.
10Units
Min. Investment

$85,000

Lice Clinics of America
Medical & Healthcare Franchise Many Cities, Many States, USA

Lice Clinics of America

Lice Clinics of America has emerged as one of the most trusted names in non-toxic lice treatment and prevention services across the United States. Built on innovation, scientific credibility, and a genuine commitment to family health, the brand has completely transformed what used to be a stressf...

2014Estd.
150Units
Min. Investment

$85,000

Let Mommy Sleep For Sale - Night Nurse & Newborn Care
Medical & Healthcare Franchise Many Cities, Many States, USA

Let Mommy Sleep For Sale - Night Nurse & Newborn Care

Let Mommy Sleep is one of America’s most trusted newborn care and overnight support brands, built on a simple yet powerful mission: to help families thrive during the exhausting early stages of parenthood. As sleep deprivation becomes a growing concern among new parents and postpartum care demand...

2010Estd.
20Units
Min. Investment

$75,000

In Home Personal Services
Medical & Healthcare Franchise Many Cities, Many States, USA

In Home Personal Services

In Home Personal Services is one of the most recognized names in the non-medical senior care sector, offering a compassionate, relationship-driven model that stands apart in an increasingly competitive home-care market. Built on the belief that seniors deserve independence, emotional support, and...

2000Estd.
20Units
Min. Investment

$75,000

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