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Top Medical & Healthcare Franchise Opportunities for Sale

Explore the best medical and healthcare franchise opportunities for sale in the USA and Canada. Discover trusted brands offering urgent care clinics, home health care, medical staffing, senior care services, telehealth platforms, physical therapy centres, and diagnostic & imaging franchises. Ideal for entrepreneurs and health-professionals seeking a high-demand, recession-resistant business model with strong recurring revenue. Compare franchise listings, review investment and regulatory details, and connect directly with franchisors providing training, compliance support, and proven systems. Start building your future with a profitable medical or healthcare franchise today.
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Profile by Sanford
Medical & Healthcare Franchise Many Cities, Many States, USA

Profile by Sanford

Profile by Sanford is a science-based, medically supported weight loss and lifestyle coaching franchise that has established a strong reputation in the U.S. health and wellness industry. Built around sustainable results rather than short-term dieting trends, the concept combines personalized nutr...

2012Estd.
150Units
Min. Investment

$150,000

Preferred Care at Home
Medical & Healthcare Franchise Many Cities, Many States, USA

Preferred Care at Home

Preferred Care at Home is a well-established, non-medical senior care franchise designed to meet one of the fastest-growing needs in the United States—aging in place. As millions of seniors choose to remain in their own homes rather than move into assisted living facilities, the demand for reliab...

1984Estd.
100Units
Min. Investment

$70,000

Physicians Weight Loss Centers
Medical & Healthcare Franchise Many Cities, Many States, USA

Physicians Weight Loss Centers

Physicians Weight Loss Centers is one of the most established physician-guided weight loss franchise concepts in the United States. Built around medically supervised programs, evidence-based nutrition, and long-term lifestyle coaching, the brand has earned a strong reputation in the growing healt...

1979Estd.
44Units
Min. Investment

$100,000

Physical Therapy NOW
Medical & Healthcare Franchise Many Cities, Many States, USA

Physical Therapy NOW

Physical Therapy NOW is a modern, patient-focused outpatient physical therapy franchise built to serve the rapidly growing rehabilitation and wellness market in the United States. The brand is centered on delivering high-quality, evidence-based physical therapy services through a streamlined clin...

2011Estd.
44Units
Min. Investment

$150,000

PharmaBox Franchise Investment & Cost Opportunity
Medical & Healthcare Franchise Many Cities, Many States, USA

PharmaBox Franchise Investment & Cost Opportunity

The PharmaBox franchise represents a modern evolution of pharmacy retail in the United States, combining healthcare access, automation, and scalable entrepreneurship. Built around smart pharmacy vending kiosks, PharmaBox delivers over-the-counter medications, health essentials, and approved welln...

2014Estd.
100Units
Min. Investment

$50,000

Passport Health Franchise Cost & Fees Opportunity
Medical & Healthcare Franchise Many Cities, Many States, USA

Passport Health Franchise Cost & Fees Opportunity

Passport Health is a highly specialized and recession-resistant franchise opportunity within the healthcare services sector. As international travel, corporate mobility, immigration, study abroad programs, and global assignments continue to increase across the United States, the demand for profes...

1994Estd.
300Units
Min. Investment

$150,000

OsteoStrong Franchise Cost & Fees Opportunities
Medical & Healthcare Franchise Many Cities, Many States, USA

OsteoStrong Franchise Cost & Fees Opportunities

The OsteoStrong franchise represents a next-generation wellness concept built around measurable, science-backed musculoskeletal health. Positioned at the intersection of preventative healthcare, longevity, and performance optimization, OsteoStrong centers focus on strengthening bones, muscles, an...

2012Estd.
200Units
Min. Investment

$250,000

OrthoNOW - Orthopedic Urgent Care
Medical & Healthcare Franchise Many Cities, Many States, USA

OrthoNOW - Orthopedic Urgent Care

OrthoNOW is a specialized orthopedic urgent care franchise built to address one of the biggest inefficiencies in the U.S. healthcare system: delayed access to orthopedic care. By combining the speed and convenience of urgent care with the expertise of orthopedic specialists, OrthoNOW clinics deli...

2011Estd.
6Units
Min. Investment

$750,000

Nuviva Medical Weight Loss
Medical & Healthcare Franchise Many Cities, Many States, USA

Nuviva Medical Weight Loss

Nuviva Medical Weight Loss is a physician-supervised medical weight loss and wellness franchise built for today’s health-conscious, results-driven consumers. The brand operates at the intersection of clinical care, lifestyle transformation, and aesthetics, offering structured programs that emphas...

2013Estd.
50Units
Min. Investment

$150,000

North Star Family Medicine
Medical & Healthcare Franchise Many Cities, Many States, USA

North Star Family Medicine

North Star Family Medicine represents a modern, patient-centered approach to primary healthcare in the United States—combining trusted family medicine principles with scalable, franchise-ready systems. Designed to meet the rising demand for accessible, preventative, and long-term care, North Star...

2010Estd.
15Units
Min. Investment

$350,000

Nora Mental Health
Medical & Healthcare Franchise Many Cities, Many States, USA

Nora Mental Health

Nora Mental Health is redefining how mental health services are delivered across the United States. Built around accessibility, clinical excellence, and a strong community-first approach, the brand provides outpatient behavioral health services that address one of the fastest-growing and most res...

2018Estd.
20Units
Min. Investment

$300,000

My Eyelab - Optical & Eye Care
Medical & Healthcare Franchise Many Cities, Many States, USA

My Eyelab - Optical & Eye Care

My Eyelab is a modern, fast-growing optical retail and eye-care franchise designed to meet the evolving needs of value-driven consumers across the United States. Built around a clear promise—quality eye care, affordable pricing, and a fast, convenient customer experience—the brand has positioned ...

2013Estd.
100Units
Min. Investment

$500,000

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