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Medical & Healthcare Franchise Opportunities Under $80k - Affordable Franchise Investment 2026

Explore proven Medical & Healthcare franchises under $80k across the USA and Canada. Find affordable, low-risk opportunities in home services, mobile businesses, cleaning, pet care, fitness, wellness, automotive, senior care, education, tutoring, kids’ activities, real estate services, marketing, retail, and food concepts. Compare investment ranges, fees, support, and territories. Ideal for entrepreneurs seeking a faster, lower-cost path to ownership in 2026
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Preferred Care at Home
Medical & Healthcare Franchise Many Cities, Many States, USA

Preferred Care at Home

Preferred Care at Home is a well-established, non-medical senior care franchise designed to meet one of the fastest-growing needs in the United States—aging in place. As millions of seniors choose to remain in their own homes rather than move into assisted living facilities, the demand for reliab...

1984Estd.
100Units
Min. Investment

$70,000

PharmaBox Franchise Investment & Cost Opportunity
Medical & Healthcare Franchise Many Cities, Many States, USA

PharmaBox Franchise Investment & Cost Opportunity

The PharmaBox franchise represents a modern evolution of pharmacy retail in the United States, combining healthcare access, automation, and scalable entrepreneurship. Built around smart pharmacy vending kiosks, PharmaBox delivers over-the-counter medications, health essentials, and approved welln...

2014Estd.
100Units
Min. Investment

$50,000

Let Mommy Sleep For Sale - Night Nurse & Newborn Care
Medical & Healthcare Franchise Many Cities, Many States, USA

Let Mommy Sleep For Sale - Night Nurse & Newborn Care

Let Mommy Sleep is one of America’s most trusted newborn care and overnight support brands, built on a simple yet powerful mission: to help families thrive during the exhausting early stages of parenthood. As sleep deprivation becomes a growing concern among new parents and postpartum care demand...

2010Estd.
20Units
Min. Investment

$75,000

In Home Personal Services
Medical & Healthcare Franchise Many Cities, Many States, USA

In Home Personal Services

In Home Personal Services is one of the most recognized names in the non-medical senior care sector, offering a compassionate, relationship-driven model that stands apart in an increasingly competitive home-care market. Built on the belief that seniors deserve independence, emotional support, and...

2000Estd.
20Units
Min. Investment

$75,000

YOLO Mentoring & Therapeutic USA
Medical & Healthcare Franchise Many Cities, Many States, USA

YOLO Mentoring & Therapeutic USA

A clear overview of your business and what makes it unique YOLO Mentoring LLC will provide superior quality services of Mentoring and Sibling Visitation to the growing need of services in the State of Florida.  Judges, attorney’s, case managers, juvenile probation officers and comm...

2015Estd.
2Units
Min. Investment

$80,000

Champion Home Health Care USA
Medical & Healthcare Franchise Many Cities, Many States, USA

Champion Home Health Care USA

Champion Home Health Care stands as a beacon of compassion and reliability in the home health care industry. With a mission to provide personalized, non-medical support, the franchise empowers seniors and individuals with disabilities to maintain independence and quality of life in the comfort of...

2008Estd.
6Units
Min. Investment

$50,000

Boost Home Healthcare in the USA
Medical & Healthcare Franchise Many Cities, Many States, USA

Boost Home Healthcare in the USA

Boost Home Healthcare is one of America’s fastest-growing senior care and home healthcare franchise brands, offering compassionate, professional, and reliable in-home medical and non-medical care services. As the U.S. population continues to age rapidly, the demand for quality home healthcare has...

2021Estd.
6Units
Min. Investment

$75,000

Azira Mental Health USA
Medical & Healthcare Franchise Many Cities, Many States, USA

Azira Mental Health USA

Azira Mental Health stands at the forefront of revolutionizing mental health care in the United States. With a commitment to providing accessible, compassionate, and innovative mental health services, Azira offers a unique opportunity for entrepreneurs to invest in a socially impactful and financ...

2019Estd.
3Units
Min. Investment

$41,300

Auxo Medical USA
Medical & Healthcare Franchise Many Cities, Many States, USA

Auxo Medical USA

Auxo Medical stands at the forefront of the medical equipment industry, offering a unique franchise opportunity that combines the sale, maintenance, and repair of new and refurbished medical equipment.With a commitment to delivering high-quality solutions to healthcare facilities nationwide, Auxo...

1998Estd.
4Units
Min. Investment

$50,000

At Your Side Home Care USA
Medical & Healthcare Franchise Many Cities, Many States, USA

At Your Side Home Care USA

At Your Side Home Care, a prominent brand under Best Life Brands, is revolutionizing in-home care by offering compassionate, personalized services that enable seniors to live independently and with dignity in their own homes. With a strong reputation for excellence, the franchise provides a prove...

1996Estd.
200Units
Min. Investment

$73,000

At Home Hearing Healthcare
Medical & Healthcare Franchise Many Cities, Many States, USA

At Home Hearing Healthcare

At Home Hearing Healthcare is a pioneering franchise in the hearing care industry, offering a unique blend of in-home and in-office audiology services. With a commitment to personalized care and the latest hearing technology, the brand has established itself as a trusted name in the United States...

2020Estd.
2Units
Min. Investment

$64,750

Assurance Home Care USA
Medical & Healthcare Franchise Many Cities, Many States, USA

Assurance Home Care USA

Assurance Home Care is a leading provider of in-home care services, dedicated to enhancing the quality of life for seniors and individuals with disabilities. With a mission centered on compassion, reliability, and personalized care, Assurance Home Care offers a franchise opportunity that combines...

2009Estd.
5Units
Min. Investment

$50,000

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